| # | Swimmer | Team | Seed | Time | Diff |
| 1 |
Gao, Sophia (11)
|
ADCPP |
2:34.91 |
2:31.14 |
-3.77 |
| 2 |
Harpootlian, Hannah R (11)
|
ADCPP |
2:46.05 |
2:39.93 |
-6.12 |
| 3 |
Kline, Keaghan E (11)
|
NESNAP |
2:52.10 |
2:49.24 |
-2.86 |
| 4 |
Smith, Lena T (11)
|
NESNAP |
2:51.93 |
2:50.18 |
-1.75 |
| 5 |
Carter, Gwendolyn S (11)
|
ADEELS |
3:16.15 |
2:54.73 |
-21.42 |
| 6 |
Donofrio, Sophia B (11)
|
ADCPP |
3:02.60 |
2:55.80 |
-6.80 |
| 7 |
Knill, Alexis A (11)
|
ADGLFY |
3:00.58 |
2:56.10 |
-4.48 |
| 8 |
McFarland, Madeline J (11)
|
ADBFIN |
2:56.87 |
2:58.04 |
1.17 |
| 9 |
Downey, Isabelle G (11)
|
ADSCHE |
2:54.95 |
3:00.57 |
5.62 |
| 10 |
Price, Catherine E (11)
|
ADSCHE |
3:03.89 |
3:03.11 |
-0.78 |
| 11 |
Boyle, Emma E (11)
|
ADSCHE |
3:11.82 |
3:06.77 |
-5.05 |
| 12 |
Mieu, Shayla S (11)
|
ADBFIN |
3:19.15 |
3:13.55 |
-5.60 |
| 13 |
Sokolewicz, Catherine N (11)
|
ADSCHE |
|
3:16.95 |
- |
| 14 |
Nicastro, Gabriella G (11)
|
NEPVA |
|
3:23.32 |
- |
| 15 |
Pezzuto, Ava R (11)
|
ADEELS |
3:54.86 |
3:24.45 |
-30.41 |
| 16 |
Reinhardt, Elina R (11)
|
ADSCHE |
|
3:37.74 |
- |
|
Banson, Marissa Belle P (11)
|
ADBFIN |
3:05.36 |
DQ |
- |